DNA Ligase ATP

ATP-dependent cellular enzyme which catalyzes DNA replication, repair and recombination through formation of internucleotide ester bonds between phosphate and deoxyribose moieties. Vertebrate cells encode three well-characterized DNA ligases, DNA ligase I, III and IV, all of which are related in structure and sequence. DNA ligases either require ATP or NAD. However, archaebacterial, viral, and some eubacterial DNA ligases are ATP-dependent.

Also Known As:

DNA Ligase I; DNA Ligase II; DNA Ligase III; DNA Ligase IIIalpha; DNA Ligase IV; DNA Ligases, ATP-Dependent; LIGIIIalpha Protein; Polydeoxyribonucleotide Synthase ATP; ATP Dependent DNA Ligase; ATP, DNA Ligase; ATP, Polydeoxyribonucleotide Synthase; ATP-Dependent DNA Ligases; DNA Ligase, ATP-Dependent; DNA Ligases, ATP Dependent; IIIalpha, DNA Ligase; Ligase ATP, DNA; Ligase I, DNA; Ligase II, DNA; Ligase III, DNA; Ligase IIIalpha, DNA; Ligase IV, DNA; Ligase, ATP-Dependent DNA; Ligases, ATP-Dependent DNA; Synthase ATP, Polydeoxyribonucleotide; ATP-Dependent DNA Ligase

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Ligases: 5708
    - Polynucleotide Ligases: 2
      - DNA Ligases: 139
        DNA Ligase ATP: 176
  - DNA Repair Enzymes: 502
    - DNA Ligases: 139
      - DNA Ligase ATP: 176

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Disease

Drug/Important Bio-Agent (IBA)